AS-OCT shows Schlemm’s canal enlargement as early sign of trabeculectomy success
Morphological changes in Schlemm’s canal, particularly its enlargement after trabeculectomy, could serve as a marker for evaluating and monitoring surgical success in patients with glaucoma, according to a study.
The study included 35 eyes from 35 patients undergoing trabeculectomy for open-angle glaucoma. Using anterior segment optical coherence tomography (AS-OCT), the researchers assessed changes in Schlemm’s canal preoperatively, and at 1 week, 1 month, and 3 months post-surgery. Measurements focused on the canal’s coronal and meridional diameters in both the nasal and temporal quadrants.
The nasal quadrant’s meridional diameter was larger than the temporal quadrant preoperatively. Significant expansion of the nasal quadrant was observed in the first week and month post-surgery, while temporal measurements showed less pronounced changes. Coronal diameter measurements also increased significantly in both quadrants at week one (nasal: P = 0.005; temporal: P = 0.023).
Reference
Sağdıç Özçelik S, Alagoz N, Yaşar T. Changes in Schlemm’s canal morphology after trabeculectomy in open angle glaucoma assessed using anterior segment optical coherence tomography. Clin Exp Optom. 2024;1-6. doi: 10.1080/08164622.2024.2400319. Epub ahead of print. PMID: 39397493.
